Please answer the following questions: (Thanks to Crinrict). What's your operating system?. Does the launcher start?.
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Are you getting any error messages?. How far do you get, try to describe what happens in as much details as possible (without getting too lenghty). Do all installed games show up in the Origin client?. Which base game version do you have:.
Which Security Software are you using (Firewall, Antivirus)?. Do you have the disc or download version or a mix?. Do you have any files with xctp in your documentselectronicartsthesims3 folder? (those are crash logs)?.
It's also good to include your DxDiag:See if this helps as well.